Dr. Spector specializes in all aspects of extirpative head and neck surgical oncology and head and neck reconstruction.
He is a member of the American Head and Neck Society Mucosal Malignancies Section, Reconstructive Head and Neck Surgery Section, and the Salivary Gland Section. He is also a member of the Michigan Work Society, Triological Society, and American Head and Neck Society, and a Fellow, American College of Surgeons. He is a member of the Cancer Center Core, Head and Neck Oncology Research Program, committee lead for the Head and Neck Oncology Program Future Directions, and a member of the Otolaryngology Clinical Competency Committee. Additionally, he is a member of the Specialized Program of Research Excellence, Head and Neck Oncology Data Access Committee, Periprocedural Safety and Quality Improvement Program, and Cancer Strategic Planning Steering Committee. He is also a member of the Centralized Otolaryngology Research Effort (CORE) Committee. Dr. Spector is an editorial board member of Plastic and Aesthetic Research and Frontiers in Oncology.
- University of Michigan, Fellowship in Head and Neck Oncology and Microvascular Reconstructive Surgery
- University of Michigan, Residency in Otolaryngology – Head and Neck Surgery
- Stritch School of Medicine, Loyola University, MD
- Quincy University, BS in Biology, Chemistry, Mathematics
Education & Training
Dr. Spector’s research interests relate to both clinical and translational questions in head and neck oncology and head and neck reconstruction. He is primarily interested in improving the overall survival of patients with head and neck cancer through outcomes research to improve patient selection and prediction of response to therapy. He has significant experience in the design, management and completion of biomarker based experiments to assess predictors of recurrence in head and neck cancer.
Dissecting the Molecular Role of HPV Integration-Associated E2 Loss in HNSCC. As Co-PI, Dr. Spector helped conceive and design the project, and will provide the clinical samples for project completion. NIH-DHHS-US- 21-PAF07958
Brenner, Chad; Mills, Ryan Edward; Spector, Matthew Edward, Co-PI
04/2022-03/2027
FOXA1 Epigenetic Mechanisms in Salivary Duct Carcinoma NIH-DHHS-US- 21-PAF04264
Co-I with Effort (Principal Investigator: Udager, Aaron Mark)
10/2021-09/2026
Identification of Genetic Drivers of Aggressive Mucoepidermoid Carcinoma NIH-DHHS-US- 21-PAF05246
Co-I with Effort (Principal Investigator: Brenner, Chad)
09/2021-08/2026
Identification of Genetic Drivers of Aggressive Mucoepidermoid Carcinoma NIH-DHHS-US- 21-PAF01726
Co-I with Effort (Principal Investigator: Brenner, Chad)
07/2021-06/2026
Extracellular Vesicle-Derived Proteins for Early Detection, Prognosis, and Post-Treatment Monitoring of Head and Neck Cancer NIH-DHHS-US- 21-PAF01509
Co-I with Effort (Principal Investigator: Walline, Heather Marie)
07/2021-06/2026